The SAFEPROCESS TC promotes on-line fault detection, isolation (FDI), estimation and diagnosis, with a view to predictive maintenance and supervision, as well as fault tolerant control. It addresses residual generation, residual evaluation, performance monitoring, statistical hypothesis testing, on-line change detection, software sensors, active input signal generation for FDI, decision making, controller reconfiguration and switching. It relies on system theory, statistics, system identification, statistical process control, artificial intelligence and optimization theory. Processes described by models qualified as linear/ non-linear, uncertain, hybrid, lumped/ distributed parameters, rule-based and discrete-event models are considered. This TC also promotes analysis tools such as failure mode and effects analysis, severity analysis and reliability theory to achieve fault tolerant designs.